Reproduction Abstracts

Introduction: Differentiation of the embryoblast and trophoblast cell lineages is an ontogenetic milestone in preimplantation embryo development. Both cell lineages are supplied with nutrients from uterine secretions, reflecting an ultrafiltrate of maternal plasma. We have recently shown that an insulin-dependent diabetes mellitus leads to maternal hyperlipidaemia and to a strong increase in intracellular lipids in trophoblast and, especially, embryoblast cells in rabbit blast...